AN UNBIASED VIEW OF PENTOBARBITAL SODIUM IN HUMANS

Check Closely (1)pentobarbital will lessen the extent or effect of fentanyl intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Closely. Coadministration of fentanyl with CYP3A4 inducers could lead to some decrease in fentanyl plasma concentrations, deficiency of efficacy or, perhaps, enhancement of a withdra